1-异氰基-4-三氟甲基苯合成路线 （共 8 条）
反应条件
1: quinoline With fluorine in chloroform T=-60°C; 2: p-(trifluoromethyl)phenyl isonitrile With trimethylsilylazide in chloroform T=-60 - 20°C;
参考文献
Kiselyov, Alexander S.
Tetrahedron Letters, 2005 , vol. 46, # 29 p. 4851 - 4854
反应条件
1: alpha-chloropyridine With fluorine in chloroform T=-78 - -60°C; 2: p-(trifluoromethyl)phenyl isonitrile With trimethylsilylazide in chloroform T=-50 - 0°C;
参考文献
Kiselyov, Alexander S.
Tetrahedron Letters, 2005 , vol. 46, # 29 p. 4851 - 4854
反应条件
2,4,6-trichloro-1,3,5-triazine; triethylamine in dichloromethane
T=50°C; 0.05 h; microwave irradiation;
参考文献
Porcheddu, Andrea; Giacomelli, Giampaolo; Salaris, Margherita
Journal of Organic Chemistry, 2005 , vol. 70, # 6 p. 2361 - 2363
反应条件
4-methyl-morpholine in dichloromethane; toluene
参考文献
Deming, Timothy J.; Novak, Bruce M.; Ziller, Joseph W.
Journal of the American Chemical Society, 1994 , vol. 116, # 6 p. 2366 - 2374
反应条件
1: 72 h / Heating
2: 65 percent / N-methylmorpholine / CH2Cl2; toluene
View Scheme
参考文献
Deming, Timothy J.; Novak, Bruce M.; Ziller, Joseph W.
Journal of the American Chemical Society, 1994 , vol. 116, # 6 p. 2366 - 2374
反应条件
1: pyridine With fluorine in chloroform
T=-78 - -60°C;
2: p-(trifluoromethyl)phenyl isonitrile With trimethylsilylazide in chloroform
T=-50 - 0°C;
参考文献
Kiselyov, Alexander S.
Tetrahedron Letters, 2005 , vol. 46, # 29 p. 4851 - 4854
反应条件
1: 2-picoline With fluorine in chloroform
T=-78 - -60°C;
2: p-(trifluoromethyl)phenyl isonitrile With trimethylsilylazide in chloroform
T=-50 - 0°C;
参考文献
Kiselyov, Alexander S.
Tetrahedron Letters, 2005 , vol. 46, # 29 p. 4851 - 4854
反应条件
1: 4-Methylpyridine With fluorine in chloroform
T=-78 - -60°C;
2: p-(trifluoromethyl)phenyl isonitrile With trimethylsilylazide in chloroform
T=-50 - 0°C;
参考文献
Kiselyov, Alexander S.
Tetrahedron Letters, 2005 , vol. 46, # 29 p. 4851 - 4854
