2-(2-Boc-氨基乙氧基)乙醇合成路线 （共 7 条）
反应条件
in chloroform T=20°C; Acylation; 1.5 h;
参考文献
Singh, Vijay; Wang, Shenliang; Kool, Eric T.
Journal of the American Chemical Society, 2013 , vol. 135, # 16 p. 6184 - 6191
反应条件
1: 2-(2-amino-ethoxy)-ethanol With sodium hydrogencarbonate in dichloromethane; water T=20°C; 0.166667 h; 2: di-tert-butyl dicarbonate in dichloromethane; water T=20°C;
参考文献
Zhao, Xuan; Bentley, Michael D.; Ren, Zhongxu; Viegas, Tacey X.
Patent: US2005/112088 A1, 2005 ;
Location in patent: Page/Page column 25-27 ;
反应条件
sodium hydroxide in tetrahydrofuran; water T=0°C; 1 h;
参考文献
Dellaria, Joseph F.; Lindstrom, Kyle J.; Dressel, Luke T.; Duffy, Daniel E.; Heppner, Philip D.; Jacobsen, John R.; Moseman, Joan T.; Moser, William H.; Radmer, Matthew R.; Stoermer, Doris; Zimmermann, Bernhard M.
Patent: US2004/10007 A1, 2004 ;
Location in patent: Page 74 ;
参考文献
Shionogi Bioresearch Corp.
Patent: US6255323 B1, 2001 ;
反应条件
pyridine in acetonitrile
参考文献
SS Pharmaceutical Co., Ltd.
Patent: US6171520 B2, 2001 ;
反应条件
1: triethylamine / dichloromethane / 0 - 20 °C / Inert atmosphere 2: sodium azide / N,N-dimethyl-formamide / 1.5 h / 90 °C 3: hydrogen / palladium 10 on activated carbon / methanol / 18.5 h / 1500.15 Torr View Scheme
反应条件
1H-imidazole; iodine in dichloromethane
T=0 - 20°C;
参考文献
3M INNOVATIVE PROPERTIES COMPANY
Patent: WO2006/86449 A2, 2006 ;
Location in patent: Page/Page column 98 ;
