hydrogen; palladium on activated charcoal in ethanol; ethyl acetate 4 h;

1: 97 percent / potassium hydride, 1,3-diaminopropane / 18 h / Ambient temperature 2: 93 percent / imidazole, / dimethylformamide / 2 h / Ambient temperature 3: 93 percent / Et3N, CuI / (Ph3P)2PdCl2 / 4 h / 50 °C 4: 93 percent / H2 / 5percent Pd-C / ethanol; ethyl acetate / 4 h View Scheme

1: 93 percent / imidazole, / dimethylformamide / 2 h / Ambient temperature 2: 93 percent / Et3N, CuI / (Ph3P)2PdCl2 / 4 h / 50 °C 3: 93 percent / H2 / 5percent Pd-C / ethanol; ethyl acetate / 4 h View Scheme

1: 93 percent / Et3N, CuI / (Ph3P)2PdCl2 / 4 h / 50 °C 2: 93 percent / H2 / 5percent Pd-C / ethanol; ethyl acetate / 4 h View Scheme