1-(6-溴-2-吡啶)-1-乙醇合成路线 （共 5 条）
反应条件
sodium tetrahydroborate in methanol T=20°C; 2 h;
参考文献
Telfer, Shane G.; Kuroda, Reiko
Chemistry - A European Journal, 2005 , vol. 11, # 1 p. 57 - 68
反应条件
1: 2,6-Dibromopyridine With n-butyllithium in hexane; dichloromethane T=-78°C; 1 h; Inert atmosphere; 2: acetaldehyde in hexane; dichloromethane T=-78 - 20°C; Inert atmosphere;
参考文献
Komanduri, Venukrishnan; Grant, Christopher D.; Krische, Michael J.
Journal of the American Chemical Society, 2008 , vol. 130, # 38 p. 12592 - 12593
反应条件
1: 1.) n-butyllithium / 1.) diethyl ether, hexane, THF, -78 deg C, 2.) diethyl ether, hexane, THF, 5-30 min 2: NaBH4 / methanol / 1 h / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry, , vol. 63, # 8 p. 2481 - 2487
参考文献
Tetrahedron Letters, , vol. 35, # 43 p. 7973 - 7976
反应条件
sulfuric acid
T=90°C; 90 h;
参考文献
Flapper, Jitte; Wormald, Philip; Lutz, Martin; Spek, Anthony L.; Van Leeuwen, Piet W. N. M.; Elsevier, Cornelis J.; Kamer, Paul C. J.
European Journal of Inorganic Chemistry, 2008 , # 31 p. 4968 - 4976
