1,3-二乙基-2-[(E,3E)-3-(1,3,3-三甲基吲哚-2-亚基)丙-1-烯基]-2H-苯并[f]苯并咪唑-1-鎓氯化物合成路线 （共 5 条）
反应条件
amberlite IRA-400 chloride ion-exchange resin 2 h; Ambient temperature;
参考文献
Lawrence; Venepalli; Appell; Goswami; Logan; Tomczuk; Yanni
Journal of Medicinal Chemistry, 1992 , vol. 35, # 7 p. 1273 - 1279
反应条件
1: 53.8 percent / potassium hydroxide / acetone / 3 h / Ambient temperature 2: 94.3 percent / 4 h / 100 °C 3: 85.4 percent / DBU / acetonitrile / 0.5 h / Heating 4: 95.6 percent / amberlite IRA-400 chloride ion-exchange resin / 2 h / Ambient temperature View Scheme
参考文献
Lawrence; Venepalli; Appell; Goswami; Logan; Tomczuk; Yanni
Journal of Medicinal Chemistry, 1992 , vol. 35, # 7 p. 1273 - 1279
反应条件
1: 68.7 percent / concd. sulfuric acid / dimethylformamide / a) 120 deg C, 2 h, b) 140 deg C, 2 h 2: 53.8 percent / potassium hydroxide / acetone / 3 h / Ambient temperature 3: 94.3 percent / 4 h / 100 °C 4: 85.4 percent / DBU / acetonitrile / 0.5 h / Heating 5: 95.6 percent / amberlite IRA-400 chloride ion-exchange resin / 2 h / Ambient temperature View Scheme
参考文献
Lawrence; Venepalli; Appell; Goswami; Logan; Tomczuk; Yanni
Journal of Medicinal Chemistry, 1992 , vol. 35, # 7 p. 1273 - 1279
反应条件
1: 94.3 percent / 4 h / 100 °C 2: 85.4 percent / DBU / acetonitrile / 0.5 h / Heating 3: 95.6 percent / amberlite IRA-400 chloride ion-exchange resin / 2 h / Ambient temperature View Scheme
参考文献
Lawrence; Venepalli; Appell; Goswami; Logan; Tomczuk; Yanni
Journal of Medicinal Chemistry, 1992 , vol. 35, # 7 p. 1273 - 1279
反应条件
1: 85.4 percent / DBU / acetonitrile / 0.5 h / Heating 2: 95.6 percent / amberlite IRA-400 chloride ion-exchange resin / 2 h / Ambient temperature View Scheme
参考文献
Lawrence; Venepalli; Appell; Goswami; Logan; Tomczuk; Yanni
Journal of Medicinal Chemistry, 1992 , vol. 35, # 7 p. 1273 - 1279
