1: 1H-imidazole 2: methanol; pyridinium p-toluenesulfonate / 6 h / 20 °C View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '110354', constants.ctx, '0')">4-(N,N-dimethlyamino)pyridine</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '19778174', constants.ctx, '0')">TEA</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1730800', constants.ctx, '0')">dichloromethane</a> <br />T=0&deg;C;&nbsp;4&nbsp;h;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: sodium hydride / 6 h / 20 &deg;C<br />2: chlorodicarbonyl(1-(isopropylamino)-2,3,4,5-tetraphenylcyclopentadienyl) ruthenium (II); Candida antarctica CAL-B lipase; potassium <i>tert</i>-butylate; potassium carbonate<br />3: methanol; potassium carbonate / 1 h<br /> <br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: sodium hydride / 6 h / 20 &deg;C<br />2: chlorodicarbonyl(1-(isopropylamino)-2,3,4,5-tetraphenylcyclopentadienyl) ruthenium (II); Candida antarctica CAL-B lipase; potassium <i>tert</i>-butylate; potassium carbonate<br />3: methanol; potassium carbonate / 1 h<br /> <br /> &nbsp;