4-氨基-6-甲基-2H-吡嗪-3-酮合成路线 （共 3 条）
反应条件
hydrazine hydrate T=150 - 160°C; 10 h;
参考文献
Gres'ko; Smolyar; Yutilov
Russian Journal of Organic Chemistry, 2001 , vol. 37, # 7 p. 1026 - 1029
反应条件
1: hydrazine hydrate / ethanol / 3 h / |Reflux 2: bromine; acetic acid / 6 h / 90 °C 3: hydrazine hydrate / 16 h / 150 - 160 °C View Scheme
参考文献
Banerjee, Abhisek; Patil, Sandip; Pawar, Mahesh Y.; Gullapalli, Srinivas; Gupta, Praveen K.; Gandhi, Maulik N.; Bhateja, Deepak K.; Bajpai, Malini; Sangana, Ramachandra Rao; Gudi, Girish S.; Khairatkar-Joshi, Neelima; Gharat, Laxmikant A.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 19 p. 6286 - 6291
反应条件
1: bromine; acetic acid / 6 h / 90 °C 2: hydrazine hydrate / 16 h / 150 - 160 °C View Scheme
参考文献
Banerjee, Abhisek; Patil, Sandip; Pawar, Mahesh Y.; Gullapalli, Srinivas; Gupta, Praveen K.; Gandhi, Maulik N.; Bhateja, Deepak K.; Bajpai, Malini; Sangana, Ramachandra Rao; Gudi, Girish S.; Khairatkar-Joshi, Neelima; Gharat, Laxmikant A.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 19 p. 6286 - 6291
