1-Boc-4-[甲氧基(甲基)氨基甲酰]哌嗪合成路线

参考文献

Shen, Dong-Ming; Shu, Min; Mills, Sander G.; Chapman, Kevin T.; Malkowitz, Lorraine; Springer, Martin S.; Gould, Sandra L.; DeMartino, Julie A.; Siciliano, Salvatore J.; Kwei, Gloria Y.; Carella, Anthony; Carver, Gwen; Holmes, Karen; Schleif, William A.; Danzeisen, Renee; Hazuda, Daria; Kessler, Joseph; Lineberger, Janet; Miller, Michael D.; Emini, Emilio A.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 4 p. 935 - 939

139290-70-31-Boc-4-[甲氧基(甲基)氨基甲酰]哌嗪

301221-79-42-溴-1-(1-boc-哌啶-4-基)乙酮

参考文献

Shankaran; Donnelly, Karla L.; Shah, Shrenik K.; Guthikonda, Ravindra N.; MacCoss, Malcolm; Mills, Sander G.; Gould, Sandra L.; Malkowitz, Lorraine; Siciliano, Salvatore J.; Springer, Martin S.; Carella, Anthony; Carver, Gwen; Hazuda, Daria; Holmes, Karen; Kessler, Joseph; Lineberger, Janet; Miller, Michael D.; Emini, Emilio A.; Schleif, William A.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 13 p. 3419 - 3424

139290-70-31-Boc-4-[甲氧基(甲基)氨基甲酰]哌嗪

154775-43-61-N-BOC-4-哌啶丙酸

参考文献

Klein, Scott I.; Molino, Bruce F.; Czekaj, Mark; Gardner, Charles J.; Chu, Valeria; Brown, Karen; Sabatino, Ralph D.; Bostwick, Jeffrey S.; Kasiewski, Charles; Bentley, Ross; Windisch, Vincent; Perrone, Mark; Dunwiddie, Christopher T.; Leadley, Robert J.
Journal of Medicinal Chemistry, 1998 , vol. 41, # 14 p. 2492 - 2502

139290-70-31-Boc-4-[甲氧基(甲基)氨基甲酰]哌嗪

137076-22-31-Boc-哌啶-4-甲醛

参考文献

Myriad Pharmaceuticals, Inc.
Patent: US2004/14763 A1, 2004 ;
Location in patent: Page 21 ;

139290-70-31-Boc-4-[甲氧基(甲基)氨基甲酰]哌嗪

140235-25-2外消旋(2,3-二甲氧基苯基)-

参考文献

Fuentes, Jose A.; Carpenter, Ian; Kann, Nina; Clarke, Matthew L.
Chemical Communications, 2013 , vol. 49, # 87 p. 10245 - 10247

100-59-4苯基氯化镁+

139290-70-31-Boc-4-[甲氧基(甲基)氨基甲酰]哌嗪

193217-39-94-亚苄基-哌啶-1-羧酸叔丁酯

参考文献

AMGEN INC.
Patent: WO2009/75857 A2, 2009 ;
Location in patent: Page/Page column 75-76 ;
WO 2009/075857 A2

139290-70-31-Boc-4-[甲氧基(甲基)氨基甲酰]哌嗪

193217-39-94-亚苄基-哌啶-1-羧酸叔丁酯

参考文献

Sheffler, Douglas J.; Nedelovych, Michael T.; Williams, Richard; Turner, Stephen C.; Duerk, Brittany B.; Robbins, Megan R.; Jadhav, Sataya B.; Niswender, Colleen M.; Jones, Carrie K.; Conn, P. Jeffrey; Daniels, R. Nathan; Lindsley, Craig W.
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 4 p. 1062 - 1066

75-16-1甲基溴化镁+

139290-70-31-Boc-4-[甲氧基(甲基)氨基甲酰]哌嗪

206989-61-9

参考文献

Shen, Dong-Ming; Shu, Min; Mills, Sander G.; Chapman, Kevin T.; Malkowitz, Lorraine; Springer, Martin S.; Gould, Sandra L.; DeMartino, Julie A.; Siciliano, Salvatore J.; Kwei, Gloria Y.; Carella, Anthony; Carver, Gwen; Holmes, Karen; Schleif, William A.; Danzeisen, Renee; Hazuda, Daria; Kessler, Joseph; Lineberger, Janet; Miller, Michael D.; Emini, Emilio A.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 4 p. 935 - 939

139290-70-31-Boc-4-[甲氧基(甲基)氨基甲酰]哌嗪

206989-61-9

参考文献

Banyu Pharmaceutical Co Ltd
Patent: US6140333 A1, 2000 ;
US 6140333 A

676-58-4甲基氯化镁+

139290-70-31-Boc-4-[甲氧基(甲基)氨基甲酰]哌嗪

206989-61-9

参考文献

MERCK and CO., INC.
Patent: WO2004/41279 A1, 2004 ;
Location in patent: Page/Page column 69 ;
WO 2004/041279 A1