1: 90 percent / tetrahydrofuran / 0.25 h / 25 °C 2: NH3 / tetrahydrofuran / 2 h / 25 °C 3: methanol / 18 h / Heating View Scheme

1: NH3 / tetrahydrofuran / 2 h / 25 °C 2: methanol / 18 h / Heating View Scheme

1: 90 percent / tetrahydrofuran / 0.25 h / 25 °C 2: NH3 / tetrahydrofuran / 2 h / 25 °C 3: methanol / 18 h / Heating View Scheme

1: 1.) Br2, 2.) Et3N / 1.) CH2Cl2, 0 deg C, 5 min, 2.) 25 deg C, 18 h 2: 90 percent / tetrahydrofuran / 0.25 h / 25 °C 3: NH3 / tetrahydrofuran / 2 h / 25 °C 4: methanol / 18 h / Heating View Scheme