3,5-二氢-3-(1-甲基乙基)-5-苯基-4H-咪唑并(4,5-c)(1,8)萘啶-4-酮合成路线 （共 3 条）
反应条件
sodium hydride 1.) DMF, 2.) DMF, RT, 12 h; Yield given. Multistep reaction;
参考文献
Kuroda, Takeshi; Suzuki, Fumio
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 8 p. 2029 - 2034
反应条件
1: 1.) 60percent NaH / 1.) DMA, 0 deg C, 2.) DMA, 100 deg C,30 min 2: 49 percent / POCl3 / 1 h / Heating 3: 86 percent / 28percent aq. NH3 / tetrahydrofuran / Ambient temperature 4: sodium hydrosulfite / ethanol; H2O / 0.17 h / 80 °C 5: 1 h / Heating 6: 1.) 60percent NaH / 1.) DMF, 0 deg C, 2.) DMF, RT, 5 h View Scheme
参考文献
Kuroda, Takeshi; Suzuki, Fumio
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 8 p. 2029 - 2034
反应条件
sodium hydride 1.) DMF, 2.) DMF, RT, 2 h; Yield given. Multistep reaction;
参考文献
Suzuki, Fumio; Kuroda, Takeshi; Kawakita, Takashi; Manabe, Haruhiko; Kitamura, Shigeto; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 26 p. 4866 - 4874
