(R)-1,2-环氧基戊烷合成路线 （共 10 条）
反应条件
potassium hydroxide T=-70°C;
参考文献
Plazinska, Anita; Pajak, Karolina; Rutkowska, Ewelina; Jimenez, Lucita; Kozocas, Joseph; Koolpe, Gary; Tanga, Mary; Toll, Lawrence; Wainer, Irving W.; Jozwiak, Krzysztof
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 1 p. 234 - 246
反应条件
sodium hydroxide T=20°C; 0.0333333 h; Inert atmosphere;
参考文献
Masuo, Ritsuki; Ohmori, Ken; Hintermann, Lukas; Yoshida, Saki; Suzuki, Keisuke
Angewandte Chemie, International Edition, 2009 , vol. 48, # 19 p. 3462 - 3465
反应条件
sodium methylate in methanol 2 h;
参考文献
MacMillan, John B.; Molinski, Tadeusz F.
Journal of the American Chemical Society, 2004 , vol. 126, # 32 p. 9944 - 9945
反应条件
C38H55CoN2O4; water optical yield given as percent ee;
参考文献
Braun, Marie-Gabrielle; Vincent, Aurelie; Boumediene, Mehdi; Prunet, Joelle
Journal of Organic Chemistry, 2011 , vol. 76, # 12 p. 4921 - 4929
反应条件
dihydrogen peroxide; [(S,S-(C6H5)2PCH(CH3)CH(CH3)P(C6H5)2)Pt(pentafluorophenyl)(OH2)]CF3SO3) in dichloromethane T=-10°C; 24 h; Title compound not separated from byproducts;
参考文献
Kubo, Takafumi; Peters, Matthew W.; Meinhold, Peter; Arnold, Frances H.
Chemistry - A European Journal, 2006 , vol. 12, # 4 p. 1216 - 1220
反应条件
1: pyridine / CH2Cl2 / 7 h / -20 °C 2: 63 percent / NaOMe / methanol / 2 h View Scheme
参考文献
MacMillan, John B.; Molinski, Tadeusz F.
Journal of the American Chemical Society, 2004 , vol. 126, # 32 p. 9944 - 9945
反应条件
1: aq. HCl; NaNO2 / 15 h / -5 °C 2: LiAlH4 / diethyl ether / -10 °C 3: KOH / 1 h / 25 °C View Scheme
参考文献
Plazinska, Anita; Pajak, Karolina; Rutkowska, Ewelina; Jimenez, Lucita; Kozocas, Joseph; Koolpe, Gary; Tanga, Mary; Toll, Lawrence; Wainer, Irving W.; Jozwiak, Krzysztof
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 1 p. 234 - 246
反应条件
1: LiAlH4 / diethyl ether / -10 °C 2: KOH / 1 h / 25 °C View Scheme
参考文献
Plazinska, Anita; Pajak, Karolina; Rutkowska, Ewelina; Jimenez, Lucita; Kozocas, Joseph; Koolpe, Gary; Tanga, Mary; Toll, Lawrence; Wainer, Irving W.; Jozwiak, Krzysztof
Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 1 p. 234 - 246
反应条件
Jacobsen hydrolytic kinetic resolution; Resolution of racemate;
参考文献
Florence, Gordon J.; Cadou, Romain F.
Tetrahedron Letters, 2010 , vol. 51, # 44 p. 5761 - 5763
反应条件
hydrogen; palladium on activated carbon; N-butylamine in methanol; water T=30°C; 50 h;
参考文献
DAISO CO., LTD.
Patent: EP1582511 A2, 2005 ;
Location in patent: Page/Page column 5 ;
