tetra(n-butyl)ammonium hydrogensulfate in N,N-dimethyl-formamide

1.1: n-Bu4NHSO4 / dimethylformamide 2.1: t-BuLi / tetrahydrofuran; pentane / 0.33 h / -78 °C 2.2: 99 percent / NH4Cl / H2O; tetrahydrofuran; pentane / -78 - 20 °C View Scheme

1.1: n-Bu4NHSO4 / dimethylformamide 2.1: t-BuLi / tetrahydrofuran; pentane / 0.33 h / -78 °C 2.2: 82 percent / tetrahydrofuran; pentane / -78 - 20 °C View Scheme

sodium hydride 1) DMF, 30 min, 2) 2 h; Yield given. Multistep reaction;