2-[3-(4-喹啉-2-基哌嗪-1-基)丙基]-[1,2,4]三唑并[4,5-a]吡啶-3-酮合成路线 (共 3 条)
反应条件
1: 83 percent / KOH / toluene / 4 h / Heating 2: 84 percent / KOH / toluene / 4 h / Heating 3: 1.) NaH / 1.) xylene, reflux, 1 h, 2.) xylene, 150 deg C, 20 h View Scheme
参考文献
Alhaider
Journal of Pharmaceutical Sciences, 1992 , vol. 81, # 1 p. 99 - 103
反应条件
1: 84 percent / KOH / toluene / 4 h / Heating 2: 1.) NaH / 1.) xylene, reflux, 1 h, 2.) xylene, 150 deg C, 20 h View Scheme
参考文献
Alhaider
Journal of Pharmaceutical Sciences, 1992 , vol. 81, # 1 p. 99 - 103
反应条件
sodium hydride 1.) xylene, reflux, 1 h, 2.) xylene, 150 deg C, 20 h; Yield given. Multistep reaction;
参考文献
Alhaider
Journal of Pharmaceutical Sciences, 1992 , vol. 81, # 1 p. 99 - 103