反式-2-乙酰基环丙烷羧酸乙酯合成路线 （共 7 条）
反应条件
tetrahydro-2H-thiopyran; copper acetylacetonate in 1,2-dichloro-ethane T=65°C; Addition; Cyclopropanation; 1 h;
参考文献
Journal of the Chemical Society, Perkin Transactions 1, , # 19 p. 3267 - 3276
反应条件
in 1,2-dichloro-ethane T=20°C; Addition; Cyclopropanation; 0.5 h;
参考文献
Journal of the Chemical Society, Perkin Transactions 1, , # 19 p. 3267 - 3276
反应条件
1: 5 N aq. NaOH / ethanol / 6 h 2: SOCl2 / Ambient temperature 3: 1.) CuI / 1.) THF, ether, -78 deg C, 30 min, 2.) THF, ether, -78 deg C, 1 h View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 41, # 3 p. 346 - 357
反应条件
1: SOCl2 / Ambient temperature 2: 1.) CuI / 1.) THF, ether, -78 deg C, 30 min, 2.) THF, ether, -78 deg C, 1 h View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 41, # 3 p. 346 - 357
反应条件
copper(l) iodide 1.) THF, ether, -78 deg C, 30 min, 2.) THF, ether, -78 deg C, 1 h; Yield given. Multistep reaction;
参考文献
Journal of Medicinal Chemistry, , vol. 41, # 3 p. 346 - 357
反应条件
in dichloromethane Heating;
参考文献
Journal of Organic Chemistry, , vol. 32, p. 3351 - 3355
反应条件
(i) CH2Cl2, (ii) <nBu4N>HSO4, aq. NaOH; Multistep reaction;
参考文献
Justus Liebigs Annalen der Chemie, , p. 1026 - 1038
