2-(7-甲氧基萘-1-基)乙胺盐酸盐合成路线 （共 35 条）
反应条件
1: With hydrogen; sodium hydroxide in methanol; water; isopropyl alcohol T=25 - 30°C; P=7500.75 Torr; 2: With hydrogenchloride in methanol; water; isopropyl alcohol T=50 - 55°C; 1 h;
参考文献
WO2014/1939 A1, ;
Page/Page column 17 ;
反应条件
hydrogenchloride in water; ethyl acetate
参考文献
US2005/182276 A1, ;
Page/Page column 6 ;
反应条件
hydrogenchloride in methanol; water 1.5 h; Reflux;
参考文献
WO2013/80095 A1, ;
Page/Page column 10; 11 ;
反应条件
hydrogenchloride in methanol; water T=30 - 70°C; 4 h;
参考文献
EP2562151 A1, ;
Paragraph 0114 ;
反应条件
tetrahydridoaluminate(1-) in diethyl ether
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 8 p. 1484 - 1486
反应条件
sulfur T=180 - 185°C; 0.5 h;
参考文献
WO2012/93402 A1, ;
Page/Page column 39 ;
反应条件
1: With hydrazine hydrate in ethanol 2 h; Reflux; 2: With hydrogenchloride in dichloromethane; ethyl acetate Product distribution / selectivity;
参考文献
EP2322508 A1, ;
Page/Page column 8 ;
反应条件
1: thionyl chloride / CHCl3 2: aq. NH4OH / diethyl ether / 0 °C 3: AlH4 / diethyl ether View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 8 p. 1484 - 1486
反应条件
1: aq. NH4OH / diethyl ether / 0 °C 2: AlH4 / diethyl ether View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 8 p. 1484 - 1486
反应条件
1: ammonium acetate / toluene / Azeotropic reflux 2: hydrogen; ammonia / Raney nickel / ethanol; water / 3 h / 40 °C / Autoclave vessel 3: hydrogenchloride / ethyl acetate / 0.5 h / 0 - 5 °C 4: sulfur / 0.5 h / 180 - 185 °C View Scheme
