反应条件
1: 3-bromoisonicotinonitrile With sodium hydride in N,N-dimethyl-formamide
T=0°C;
2: oxyacetic acid ethyl ester in N,N-dimethyl-formamide
T=20°C; 1 h; Product distribution / selectivity;
参考文献
Miknis, Greg; Lyssikatos, Joseph P.; Laird, Ellen; Tarlton, Eugene; Buckmelter, Alexandre J.; Ren, Li; Rast, Bryson; Schlacter, Stephen T.; Wenglowsky, Steven Mark
Patent: US2007/49603 A1, 2007 ;
Location in patent: Page/Page column 49 ;
US 20070049603 A1
