反应条件
1: 1-amino-4-methylsulphonylbenzene With trimethylaluminum in dichloromethane; toluene T=-10 - 20°C; 1.08333 h; Inert atmosphere; 2: methyl 4-cyano-5-[(3,5-dichloropyridin-4-yl)thio]thiophene-2-carboxylate in dichloromethane; toluene T=20°C; Reflux; 3: With hydrogenchloride in dichloromethane; toluene 0.5 h;
参考文献
Weinstock, Joseph; Wu, Jian; Cao, Ping; Kingsbury, William D.; McDermott, Jeffrey L.; Kodrasov, Matthew P.; McKelvey, Devin M.; Suresh Kumar, K. G.; Goldenberg, Seth J.; Mattern, Michael R.; Nicholson, Benjamin
Medicinal Chemistry letters, 2012 , vol. 3, # 10 p. 789 - 792,4
Title/Abstract Full Text Show Details
Weinstock, Joseph; Wu, Jian; Cao, Ping; Kingsbury, William D.; McDermott, Jeffrey L.; Kodrasov, Matthew P.; McKelvey, Devin M.; Suresh Kumar; Goldenberg, Seth J.; Mattern, Michael R.; Nicholson, Benjamin
ACS Medicinal Chemistry Letters, 2012 , vol. 3, # 10 p. 789 - 792
