iodine; iodic acid; acetic acid; sulfuric acid in water T=70°C; 3 h;

1.1: n-BuLi / diethyl ether / -78 - 20 °C 1.2: 99 percent / diethyl ether / -78 - 20 °C 2.1: 93 percent / I2; HIO3; CH3COOH / H2SO4 / H2O / 3 h / 70 °C View Scheme

1: 2-methyl-3-iodobenzothiophene With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 1 h; Inert atmosphere; 2: 1,2,3,3,4,4,5,5-octafluorocyclopentene in tetrahydrofuran; hexane T=-78 - 20°C; 1 h; Inert atmosphere;