1: boron trifluoride diethyl etherate; N-bromosuccinmide / acetonitrile / -15 - 5 °C 2: sodium ethanolate / tetrahydrofuran; ethanol / 2 h / 20 °C 3: tetrahydrofuran / 10 h / 70 °C 4: trifluoroacetic acid / dichloromethane / 2 h / 10 - 20 °C 5: triethylamine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / tetrahydrofuran; N,N-dimethyl-formamide / 10 h / 20 °C View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11343411', constants.ctx, '0')">tris-(dibenzylideneacetone)dipalladium⁽⁰⁾</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '605301', constants.ctx, '0')">N-ethyl-N,N-diisopropylamine</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '7085968', constants.ctx, '0')">9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102551', constants.ctx, '0')">1,4-dioxane</a> <br />T=100&deg;C;&nbsp;10&nbsp;h;&nbsp;&nbsp;Inert atmosphere;&nbsp;<br /> &nbsp;