反应条件
1: 5-(2-ethoxy-5-iodophenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one With 1,10-phenanthroline; K2S2O5; tetraethylammonium bromide; sodium formate; palladium diacetate; triphenylphosphine in dimethyl sulfoxide T=70°C; 2 h; Inert atmosphereMicrowave irradiation; 2: 1-methyl-piperazine With N-bromosuccinmide in tetrahydrofuran; dimethyl sulfoxide T=0 - 23°C; 0.5 h; Inert atmosphere; chemoselective reaction;
参考文献
Shavnya, Andrei; Coffey, Steven B.; Smith, Aaron C.; Mascitti, Vincent
Organic Letters, 2013 , vol. 15, # 24 p. 6226 - 6229
