4-硝基-5-丙基-1H-吡唑-3-羧酰胺合成路线 (共 5 条)
反应条件
thionyl chloride in methanol; dichloromethane
参考文献
Cell Pathways, Inc.
Patent: US6200980 B1, 2001 ;
参考文献
Haning, Helmut; Niewoehner, Ulrich; Schenke, Thomas; Lampe, Thomas; Hillisch, Alexander; Bischoff, Erwin
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 17 p. 3900 - 3907
反应条件
1: HNO3; H2SO4 2: NH3 View Scheme
参考文献
Haning, Helmut; Niewoehner, Ulrich; Schenke, Thomas; Lampe, Thomas; Hillisch, Alexander; Bischoff, Erwin
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 17 p. 3900 - 3907
反应条件
1: N2H2 2: NaOH 3: HNO3; H2SO4 4: NH3 View Scheme
参考文献
Haning, Helmut; Niewoehner, Ulrich; Schenke, Thomas; Lampe, Thomas; Hillisch, Alexander; Bischoff, Erwin
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 17 p. 3900 - 3907
反应条件
1: SnCl2 2: NEt3; DMAP / CH2Cl2 3: NaOH / ethanol View Scheme
参考文献
Haning, Helmut; Niewoehner, Ulrich; Schenke, Thomas; Lampe, Thomas; Hillisch, Alexander; Bischoff, Erwin
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 17 p. 3900 - 3907