3-(6,7-二氢-1-甲基-7-氧代-3-丙基-1H-吡唑O-(4-3-D)-嘧啶-5合成路线

139756-21-15-(2-乙氧苯基)-1-甲基-3-丙基-1,6-二氢-7H-吡唑并[4,3-d]嘧啶-7-酮

139756-22-23-(6,7-二氢-1-甲基-7-氧代-3-丙基-1H-吡唑O-(4-3-D)-嘧啶-5

参考文献

Flores Toque, Haroldo A.; Priviero, Fernanda B. M.; Teixeira, Cleber E.; Perissutti, Elisa; Fiorino, Ferdinando; Severino, Beatrice; Frecentese, Francesco; Lorenzetti, Raquel; Baracat, Juliana S.; Santagada, Vincenzo; Caliendo, Giuseppe; Antunes, Edson; De Nucci, Gilberto
Journal of Medicinal Chemistry, 2008 , vol. 51, # 9 p. 2807 - 2815

5308-25-8N-乙基哌嗪+

139756-22-23-(6,7-二氢-1-甲基-7-氧代-3-丙基-1H-吡唑O-(4-3-D)-嘧啶-5

642928-07-2高西地那非

参考文献

Kumar, Indukuri V.S.; Ramanjaneyulu, Gorantla S.; Bindu, Vurimindi H.
Letters in Organic Chemistry, 2011 , vol. 8, # 9 p. 668 - 673

103-76-41-(2-羟乙基)哌嗪+

139756-22-23-(6,7-二氢-1-甲基-7-氧代-3-丙基-1H-吡唑O-(4-3-D)-嘧啶-5

139755-85-4羟基高西地那非

参考文献

Flores Toque, Haroldo A.; Priviero, Fernanda B. M.; Teixeira, Cleber E.; Perissutti, Elisa; Fiorino, Ferdinando; Severino, Beatrice; Frecentese, Francesco; Lorenzetti, Raquel; Baracat, Juliana S.; Santagada, Vincenzo; Caliendo, Giuseppe; Antunes, Edson; De Nucci, Gilberto
Journal of Medicinal Chemistry, 2008 , vol. 51, # 9 p. 2807 - 2815

109-01-3N-甲基哌嗪+

139756-22-23-(6,7-二氢-1-甲基-7-氧代-3-丙基-1H-吡唑O-(4-3-D)-嘧啶-5

139755-83-2西地那非

参考文献

TEVA PHARMACEUTICAL INDUSTRIES LTD.; TEVA PHARMACEUTICALS USA, INC.
Patent: WO2005/67936 A2, 2005 ;
Location in patent: Page/Page column 10-11 ;