1: With trichlorophosphate T=20 - 85°C; 2: With potassium carbonate in water pH=9 - 10; Product distribution / selectivity;

1.1: trichlorophosphate / 20 - 85 °C 1.2: pH 9 - 10 2.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / 4-(N,N-dimethlyamino)pyridine / 1-methyl-pyrrolidin-2-one / 0.5 h 2.2: 4.5 h / 20 - 85 °C 3.1: N-bromosuccinmide; ammonium acetate / dichloromethane / 4 h 3.2: pH 10 - 11 4.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / N,N-dimethyl-formamide / 1 h / 20 °C 4.2: 24.5 h / 100 - 110 °C 5.1: sodium hydroxide; water / isopropyl alcohol / 5.5 h / 20 - 75 °C View Scheme