1-叠氮-1-脱氧-β-D-吡喃葡萄糖苷四乙酸酯合成路线 （共 38 条）
反应条件
tetra-N-butylammonium azide in tetrahydrofuran 60 h; Reflux;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 20, # 14 p. 4263 - 4265
反应条件
tin(IV) chloride in dichloromethane T=20°C; 18 h;
参考文献
Kim, In-Hae; Nishi, Kosuke; Tsai, Hsing-Ju; Bradford, Tanya; Koda, Yasuko; Watanabe, Takaho; Morisseau, Christophe; Blanchfield, Joanne; Toth, Istvan; Hammock, Bruce D.
Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 1 p. 312 - 323
反应条件
trimethylsilylazide; tetrabutyl ammonium fluoride in tetrahydrofuran
参考文献
University of Maryland
Patent: US6414173 B1, 2002 ;
反应条件
tetra-N-butylammonium azide in dichloromethane
参考文献
Meloncelli, Peter J.; Martin, Alan D.; Lowary, Todd L.
Carbohydrate Research, 2009 , vol. 344, # 9 p. 1110 - 1122
反应条件
trimethylsilylazide; tetra-n-butylammonium difluorotriphenylsilicate(IV) in tetrahydrofuran T=65°C; Substitution; hydrolysis; 20 h;
参考文献
Journal of Organic Chemistry, , vol. 64, # 26 p. 9724 - 9726
反应条件
pyridine T=20°C; 24 h;
参考文献
Tetrahedron Letters, , vol. 43, # 22 p. 4021 - 4022
反应条件
trimethylsilylazide; tin(IV) chloride in dichloromethane T=20°C; 12 h;
参考文献
Journal of the Korean Chemical Society, , vol. 54, # 5 p. 650 - 652
反应条件
sodium azide in N,N-dimethyl-formamide 1) 50 deg C, 2 h, 2) 70 deg C, 1 h;
参考文献
Sabesan; Neira
Carbohydrate Research, 1992 , vol. 223, p. 169 - 185
反应条件
1: pyridine 2: HBr / acetic acid 3: TMS-N3; TBAF / tetrahydrofuran View Scheme
参考文献
Journal of the Chemical Society. Perkin Transactions 1, , # 8 p. 1042 - 1049
反应条件
1: 93 percent / pyridine / CH2Cl2 / -20 - -10 °C 2: 1) sodium azide, 2) pyridine / 1) 2-methoxyethanol, 100 deg C, overnight, 2) 2 h View Scheme
参考文献
Carbohydrate Research, , vol. 210, p. 333 - 337
