2-甲基-5-乙烯基吡啶合成路线 （共 24 条）
反应条件
sodium T=100°C; 7 h;
参考文献
Gao, Mingzhang; Wang, Min; Hutchins, Gary D.; Zheng, Qi-Huang
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 8 p. 2529 - 2532
反应条件
1: KMnO4, KOH / acetone; H2O / 2 h / 30 °C 2: Heating 3: 76 percent / saturated aq. NH3 / 24 h / Ambient temperature View Scheme
参考文献
Bossaerts, Jan D.; Dommisse, Roger A.; Alderweireldt, Frank C.; Geerlings, Paul
Journal of Chemical Research, Miniprint, 1987 , # 9 p. 2360 - 2384
反应条件
sodium hydride in dimethyl sulfoxide T=120°C; 48 h;
参考文献
MEDIVATION TECHNOLOGIES, INC.
Patent: WO2009/55828 A1, 2009 ;
Location in patent: Page/Page column 254 ;
WO 2009/055828 A1
反应条件
1: With 9-bora-bicyclo[3.3.1]nonane in tetrahydrofuran T=0°C; RefluxInert atmosphere; 2: With dihydrogen peroxide in tetrahydrofuran; water 1 h; Inert atmosphere;
参考文献
Dong, Huijun; Latka, Regina T.; Driver, Tom G.
Organic Letters, 2011 , vol. 13, # 10 p. 2726 - 2729
反应条件
sodium hydroxide; dimethylsulfide borane complex; dihydrogen peroxide 1.) THF, 65 deg C, 9 h; other vinyl and propenyl heterocycles; other pyridine-BF3 complexes; other hydroborating agents; var. temp. and time; Product distribution;
参考文献
Journal of Organic Chemistry, , vol. 51, # 4 p. 439 - 445
反应条件
potassium permanganate in water T=98°C; 3.15 h;
参考文献
Pharmaceutical Chemistry Journal, , vol. 26, # 11/12 p. 894 - 896
Khimiko-Farmatsevticheskii Zhurnal, , vol. 26, # 11-12 p. 81 - 83
反应条件
sodium hydroxide; dimethylsulfide borane complex; dihydrogen peroxide 1.) THF, 65 deg C, 9 h; other vinyl and propenyl heterocycles; other pyridine-BF3 complexes; other hydroborating agents; var. temp. and time; Product distribution;
参考文献
Journal of Organic Chemistry, , vol. 51, # 4 p. 439 - 445
反应条件
1.1: 9-bora-bicyclo[3.3.1]nonane / tetrahydrofuran / 0 °C / Reflux; Inert atmosphere 1.2: 1 h / Inert atmosphere 2.1: phosphorus tribromide / diethyl ether / 3 h / 0 °C / Inert atmosphere View Scheme
参考文献
Dong, Huijun; Latka, Regina T.; Driver, Tom G.
Organic Letters, 2011 , vol. 13, # 10 p. 2726 - 2729
反应条件
sodium hydroxide; dimethylsulfide borane complex; dihydrogen peroxide 1.) THF, 65 deg C, 9 h; other vinyl and propenyl heterocycles; other pyridine-BF3 complexes; other hydroborating agents; var. temp. and time; Product distribution;
参考文献
Journal of Organic Chemistry, , vol. 51, # 4 p. 439 - 445
反应条件
1: KMnO4, KOH / acetone; H2O / 2 h / 30 °C 2: Heating View Scheme
参考文献
Bossaerts, Jan D.; Dommisse, Roger A.; Alderweireldt, Frank C.; Geerlings, Paul
Journal of Chemical Research, Miniprint, 1987 , # 9 p. 2360 - 2384
