2-(喹啉-4-基)乙腈合成路线 （共 10 条）
反应条件
1: With lithium cyanide in tetrahydrofuran T=20°C; 2: With samarium diiodide; tert-butyl alcohol in tetrahydrofuran T=20°C;
参考文献
Engler, Thomas A.; Furness, Kelly; Malhotra, Sushant; Diefenbacher, Clive; Clayton, Joshua R.
Tetrahedron Letters, 2003 , vol. 44, # 14 p. 2903 - 2905
反应条件
in N,N-dimethyl-formamide T=20 - 80°C;
参考文献
WO2009/114180 A1, ;
Page/Page column 85-86 ;
反应条件
sodium cyanide in N,N-dimethyl-formamide T=20°C;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 18, # 15 p. 4388 - 4392
参考文献
Justus Liebigs Annalen der Chemie, , vol. 529, p. 266,272
反应条件
Pd-BaSO4; ethanol Hydrogenation;
参考文献
Archiv der Pharmazie (Weinheim, Germany), , vol. 290, p. 218,222
反应条件
1: aqueous KCN; diethyl ether 2: palladium/BaSO4; ethanol / Hydrogenation View Scheme
参考文献
Archiv der Pharmazie (Weinheim, Germany), , vol. 290, p. 218,222
反应条件
1: aqueous NaOH 2: acetic acid anhydride / Erhitzen auf Siedetemperatur View Scheme
参考文献
Justus Liebigs Annalen der Chemie, , vol. 529, p. 266,272
反应条件
diethyl ether; sodium N-methylanilide
参考文献
Chemische Berichte, , vol. 85, p. 397,406
反应条件
1) DMF, 120 deg C 2) water, stand overnight; Yield given. Multistep reaction;
参考文献
Journal of Heterocyclic Chemistry, , vol. 24, p. 1467 - 1472
参考文献
Borsche; Buetschli
Justus Liebigs Annalen der Chemie, 1937 , vol. 529, p. 266,272
