反应条件
1: BBr3 / CHCl3 / 0.25 h / Ambient temperature
2: resolution of the racemate via salt with (-)-O,O'-dibenzoyl-L-tartaric acid
3: HCl (g), Zn / diethyl ether
View Scheme
参考文献
Bertha, Craig M.; Mattson, Mariena V.; Flippen-Anderson, Judith L.; Rothman, Richard B.; Xu, Heng; et al.
Journal of Medicinal Chemistry, 1994 , vol. 37, # 19 p. 3163 - 3170
