1: 2-aminopyridine With potassium carbonate in 1,4-dioxane 0.75 h; 2: phenyl(phenylethynyl)iodonium trifluoroacetate in 1,4-dioxane T=20°C; DarknessInert atmosphere; regioselective reaction;

1: 2-aminopyridine With potassium carbonate in o-di-fluorobenzene 0.75 h; 2: phenyl(phenylethynyl)iodonium trifluoroacetate in o-di-fluorobenzene T=20°C; DarknessInert atmosphere; SolventReagent/catalystConcentration; Overall yield = 55 percent; regioselective reaction;

water in chloroform 2 h; Reflux;

1: 2-aminopyridine With potassium carbonate in o-di-fluorobenzene 0.75 h; 2: phenyl(phenylethynyl)iodonium trifluoroacetate in o-di-fluorobenzene T=20°C; DarknessInert atmosphere; SolventReagent/catalystConcentration; Overall yield = 55 percent; regioselective reaction;