反应条件
1: N-ethyl-N,N-diisopropylamine; 1-hydroxy-7-aza-benzotriazole; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / dichloromethane / 15 h / 0 - 25 °C / |Inert atmosphere 2: dichloromethane / 3 h / 0 - 25 °C / |Inert atmosphere 3: triethylamine / dichloromethane / 15 h / 0 - 25 °C / |Inert atmosphere 4: lithium hexamethyldisilazane; sulfur / tetrahydrofuran / 2.08 h / 25 °C / |Inert atmosphere View Scheme
参考文献
Nicolaou, K. C.; Lu, Min; Totokotsopoulos, Sotirios; Heretsch, Philipp; Giguere, Denis; Sun, Ya-Ping; Sarlah, David; Nguyen, Thu H.; Wolf, Ian C.; Smee, Donald F.; Day, Craig W.; Bopp, Selina; Winzeler, Elizabeth A.
Journal of the American Chemical Society, 2012 , vol. 134, # 41 p. 17320 - 17332,13
Title/Abstract Full Text Show Details
Nicolaou; Lu, Min; Totokotsopoulos, Sotirios; Heretsch, Philipp; Giguere, Denis; Sun, Ya-Ping; Sarlah, David; Nguyen, Thu H.; Wolf, Ian C.; Smee, Donald F.; Day, Craig W.; Bopp, Selina; Winzeler, Elizabeth A.
Journal of the American Chemical Society, 2012 , vol. 134, # 41 p. 17320 - 17332