iodine; sodium hydrogencarbonate in 1-methyl-pyrrolidin-2-one 4 h; Reflux;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '8128150', constants.ctx, '0')">sodium hydroxide</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1718733', constants.ctx, '0')">ethanol</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '3587155', constants.ctx, '0')">water</a> <br />T=0 - 20&deg;C;&nbsp;20&nbsp;h;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 &deg;C<br />1.2: 1 h / 0 &deg;C<br />2.1: sodium hydroxide / ethanol; water / 20 h / 0 - 20 &deg;C<br /> <br /> &nbsp;