1.1: hydrogenchloride; water / dichloromethane / 0 - 30 °C / pH 2 - 2.5 2.1: potassium iodide / N,N-dimethyl-formamide / 0.75 h / 25 - 65 °C / Inert atmosphere 2.2: 0.5 h / 60 - 65 °C 2.3: 0.5 h / 60 - 65 °C 3.1: dichloromethane / 3.25 h / 15 - 20 °C 4.1: zinc oxide / toluene / 2 h / 25 - 30 °C / Inert atmosphere 4.2: 12 h 5.1: hydrogenchloride; water / acetonitrile / 4 h / -10 °C 6.1: sodium tetrahydroborate; diethyl methoxy borane; methanol / ethyl acetate; tetrahydrofuran / 5 h / -80 - -75 °C / Inert atmosphere View Scheme