反应条件
1: 4-(N,N-dimethlyamino)pyridine; dicyclohexyl-carbodiimide / chloroform / 12 h / 0 - 20 °C 2: N-ethyl-N,N-diisopropylamine / chloroform / 40 h / 20 °C 3: recombinant human acid ceramidase / aq. acetate buffer / 2.5 h / 37 °C / |Enzymatic reaction View Scheme
参考文献
Bhabak, Krishna P.; Proksch, Denny; Redmer, Susanne; Arenz, Christoph
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 20 p. 6154 - 6161
