sodium methylate in tetrahydrofuran; methanol T=20°C; 5 h; chemoselective reaction;

<b>Multi-step reaction with 2 steps<br /> </b>1: triethylamine / tetrahydrofuran / 2 h / 20 &deg;C<br />2: [Pd(PPh₃)₂(OAc)₂]; tert.-butylhydroperoxide / acetonitrile; decane / 24 h / 120 &deg;C<br /> <br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: thionyl chloride / N,N-dimethyl-formamide / 0.5 h / 20 &deg;C<br />2: triethylamine / tetrahydrofuran / 2 h / 20 &deg;C<br />3: [Pd(PPh₃)₂(OAc)₂]; tert.-butylhydroperoxide / acetonitrile; decane / 24 h / 120 &deg;C<br /> <br /> &nbsp;