N-叔-丁基氧羰基-D-赤式-二氢-D-鞘氨醇合成路线 （共 8 条）
反应条件
hydrogen; palladium dihydroxide in methanol T=20°C; P=760 Torr; 15 h;
参考文献
Yun, Jung Min; Sim, Tae Bo; Hahm, Heung Sik; Lee, Won Koo; Ha, Hyun-Joon
Journal of Organic Chemistry, 2003 , vol. 68, # 20 p. 7675 - 7680
反应条件
toluene-4-sulfonic acid in methanol 5 h; Ambient temperature;
参考文献
Mori, Kenji; Uenishi, Keiji
Liebigs Annalen der Chemie, 1994 , # 1 p. 41 - 48
反应条件
1: 4.40 g / H2 / PtO2 / ethyl acetate / 1 h / Ambient temperature 2: 85 percent / p-TsOH*H2O / methanol / 5 h / Ambient temperature View Scheme
参考文献
Yoshida, Jun; Nakagawa, Masako; Seki, Hiroko; Hino, Tohru
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 3 p. 343 - 350
反应条件
1: 86 percent / N-methylmorpholine; 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride / CH2Cl2 / 1.58 h / -15 °C 2: 73 percent / s-BuMgCl / tetrahydrofuran; diethyl ether / -15 - 20 °C 3: 98 percent / LiAl(O-t-Bu)3H / ethanol / 6 h / -78 °C View Scheme
参考文献
So, Regina C.; Ndonye, Rachel; Izmirian, Douglas P.; Richardson, Stewart K.; Guerrera, Robyn L.; Howell, Amy R.
Journal of Organic Chemistry, 2004 , vol. 69, # 9 p. 3233 - 3235
反应条件
1: 73 percent / s-BuMgCl / tetrahydrofuran; diethyl ether / -15 - 20 °C 2: 98 percent / LiAl(O-t-Bu)3H / ethanol / 6 h / -78 °C View Scheme
参考文献
So, Regina C.; Ndonye, Rachel; Izmirian, Douglas P.; Richardson, Stewart K.; Guerrera, Robyn L.; Howell, Amy R.
Journal of Organic Chemistry, 2004 , vol. 69, # 9 p. 3233 - 3235
反应条件
hydrogenchloride in ethyl acetate 0.5 h;
参考文献
Mori, Kenji; Uenishi, Keiji
Liebigs Annalen der Chemie, 1994 , # 1 p. 41 - 48
反应条件
hydrogenchloride in ethyl acetate 0.5 h;
参考文献
Mori, Kenji; Uenishi, Keiji
Liebigs Annalen der Chemie, 1994 , # 1 p. 41 - 48
反应条件
hydrogenchloride in ethyl acetate 0.5 h;
参考文献
Mori, Kenji; Uenishi, Keiji
Liebigs Annalen der Chemie, 1994 , # 1 p. 41 - 48
