1: SOCl2 / dimethylformamide / Heating 2: (i-Pr)2NEt / tetrahydrofuran / 48 h / 25 °C 3: KOMe / various solvent(s) / 275 °C 4: NaH / dimethylformamide / Ambient temperature View Scheme
参考文献
Klunder, Janice M.; Hargrave, Karl D.; West, MaryAnn; Cullen, Ernest; Pal, Kollol; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 10 p. 1887 - 1897