[Ru(II)(η6-benzene)(μ-Cl)Cl]2; (S)-(-)-α,α-diphenyl-2-pyrrolidinemethanol; sodium formate in acetonitrile T=20 - 30°C; 48 h; enantioselective reaction;

in N,N-dimethyl-formamide T=140°C; 16 h;

1: (S)-1-(6-amino-9H-purin-9-yl) propan-2-ol With Mg(O-t-Bu)2 in N,N-dimethyl-formamide T=20°C; 1 h; Inert atmosphere; 2: diethyl p-toluenesulfonyloxymethylphosphonate in N,N-dimethyl-formamide T=35°C; 20 h; Inert atmosphere;