1-((4-甲氧基苯基)甲基)-1H-吡咯-2,5-二酮合成路线 （共 6 条）
反应条件
1,1,1,3,3,3-hexamethyl-disilazane; zinc(II) chloride in toluene 2 h; Heating;
参考文献
Muramatsu, Takayuki; Yamashita, Sho; Nakamura, Yumiko; Suzuki, Masahisa; Mase, Nobuyuki; Yoda, Hidemi; Takabe, Kunihiko
Tetrahedron Letters, 2007 , vol. 48, # 51 p. 8956 - 8959
参考文献
Topo Target ApS
Patent: US2003/32625 A1, 2003 ;
反应条件
triphenylphosphine; diethylazodicarboxylate in tetrahydrofuran T=20°C; Mitsunobu reaction; 24 h;
参考文献
Martinez, Ana; Alonso, Mercedes; Castro, Ana; Dorronsoro, Isabel; Gelpi, J. Luis; Luque, F. Javier; Perez, Conception; Moreno, Francisco J.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 23 p. 7103 - 7112
反应条件
1.1: hydroxylamine hydrochloride; sodium carbonate / ethanol / 20 °C 2.1: palladium 10 on activated carbon; hydrogen / ethanol / 20 °C 3.1: diethyl ether / 1 h / 20 °C 3.2: 6 h / 70 °C View Scheme
参考文献
Puerto Galvis, Carlos E.; Kouznetsov, Vladimir V.
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 3 p. 407 - 411
反应条件
1.1: palladium 10 on activated carbon; hydrogen / ethanol / 20 °C 2.1: diethyl ether / 1 h / 20 °C 2.2: 6 h / 70 °C View Scheme
参考文献
Puerto Galvis, Carlos E.; Kouznetsov, Vladimir V.
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 3 p. 407 - 411
反应条件
acetic acid Yield given;
参考文献
Cechinel Filho; Pinheiro; Nunes; Yunes; Bella Cruz; Moretto
Farmaco, 1994 , vol. 49, # 10 p. 675 - 677
