2-(羟基甲基)-4-碘苯酚合成路线 （共 9 条）
反应条件
1: With dimethylsulfide borane complex in tetrahydrofuran T=0 - 20°C; 4 h; Heating / reflux; 2: With hydrogenchloride in tetrahydrofuran; water T=20°C;
参考文献
MERCK SHARP and DOHME LIMITED; LADDUWAHETTY, Tamara
Patent: WO2006/100519 A1, 2006 ;
Location in patent: Page/Page column 15 ;
WO 2006/100519 A1
反应条件
dimethylsulfide borane complex in tetrahydrofuran 1 h;
参考文献
Smith, Mark E.B.; Gunn, Richard M.; Rosivatz, Evelyn; Mak, Lok H.; Woscholski, Ruediger; Hailes, Helen C.
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 14 p. 4917 - 4927
反应条件
in ethylene glycol dimethyl ether; xylene T=135°C; 12 h;
参考文献
Casiraghi, Giovanni; Casnati, Giuseppe; Puglia, Giuseppe; Sartori, Giovanni
Synthesis, 1980 , # 2 p. 124 - 125
参考文献
Visser
Archiv der Pharmazie (Weinheim, Germany), 1897 , vol. 235, p. 547
参考文献
Bajwa, Naval; Jennings, Michael P.
Journal of Organic Chemistry, 2006 , vol. 71, # 9 p. 3646 - 3649
反应条件
lithium aluminium tetrahydride in diethyl ether 2 h; Heating;
参考文献
Gaux,B.; le Henaff,P.
Bulletin de la Societe Chimique de France, 1974 , p. 505 - 509
反应条件
ethanol; iodine; mercury(II) oxide Trennung durch Behandlung mit Sodaloesung;
参考文献
Seidel
Journal fuer Praktische Chemie (Leipzig), 1898 , vol. <2>57, p. 205
Journal fuer Praktische Chemie (Leipzig), 1899 , vol. <2>59, p. 114
参考文献
Seidel
Journal fuer Praktische Chemie (Leipzig), 1898 , vol. <2>57, p. 205
Journal fuer Praktische Chemie (Leipzig), 1899 , vol. <2>59, p. 114
反应条件
in ethyl acetate; acetone
参考文献
G.D. Searle and Co.
Patent: US6034256 A1, 2000 ;
Title/Abstract Full Text Show Details
G.D. Searle and Co.
Patent: US6077850 A1, 2000 ;
