4-氯-N，N-二甲基苯甲酰胺合成路线 （共 33 条）
反应条件
1: 1.) lithium diisopropylamide / 2.) 5 h 2: 2n HCl View Scheme
参考文献
Boche, Gernot; Bosold, Ferdinand; Niessner, Manfred
Tetrahedron Letters, 1982 , vol. 23, # 32 p. 3255 - 3256
反应条件
1: 98 percent / pyridine / 24 h / Ambient temperature 2: 270 - 280 °C / 0.7 Torr View Scheme
参考文献
Schroth, Werner; Krieg, Reimar; Kluge, Helmut; Gaebler, Michael
Zeitschrift fuer Chemie (Stuttgart, Germany), 1985 , vol. 25, # 11 p. 398 - 399
参考文献
Kirsanow; Solotow
Zhurnal Obshchei Khimii, 1951 , vol. 21, p. 1166,1168; engl. Ausg. S. 1273, 1275
反应条件
sodium methylate in methanol T=25°C; 648 h; Equilibrium constant;
参考文献
Guthrie, J. Peter; Pike, David C.; Lee, Yiu-Chung
Canadian Journal of Chemistry, 1992 , vol. 70, # 6 p. 1671 - 1683
反应条件
(i) THF, (ii) (heating); Multistep reaction;
参考文献
Motoki,S.; Kagami,H.
Journal of Organic Chemistry, 1976 , vol. 41, p. 2759 - 2762
反应条件
in chloroform-d1 T=70°C; k = 2.2E-6/sec; Rate constant;
参考文献
Symes, Jill; Modro, Tomasz A.
Canadian Journal of Chemistry, 1986 , vol. 64, p. 1702 - 1708
反应条件
1: With diisobutylaluminium hydride in tetrahydrofuran; hexane T=-78 - -40°C; Inert atmosphere; 2: With ammonia; iodine in tetrahydrofuran; hexane; water T=0 - 20°C; Inert atmosphere;
参考文献
Suzuki, Yusuke; Yoshino, Takumi; Moriyama, Katsuhiko; Togo, Hideo
Tetrahedron, 2011 , vol. 67, # 21 p. 3809 - 3814
反应条件
in tetrahydrofuran 1 h; Inert atmosphere;
参考文献
Rao, G. Venkateswara; Swamy, B. Narayana; Kumar, P. Hareesh; Reddy, G. Chandrasekara
Synthetic Communications, 2009 , vol. 39, # 10 p. 1835 - 1846
反应条件
Ammonium O,O'-diethyl phosphorodithioate in toluene 6 h; Reflux;
参考文献
Kaboudin, Babak; Malekzadeh, Leila
Synlett, 2011 , # 19 art. no. D25711ST, p. 2807 - 2810
反应条件
NaOAc·3H2O in anhydrous dichloroethane; water; 1,2-dichloro-ethane
参考文献
McNeil Laboratories, Inc.
Patent: US4002643 A1, 1977 ;
