4-(3,4-二氯苯)-1,2,3,4-四氢-N-甲基-1-萘胺合成路线 （共 10 条）
反应条件
1: With potassium hydroxide in methanol T=25 - 30°C; 24 h; 2: With sodium tetrahydroborate in methanol T=-5 - 25°C; 12 - 14 h;
参考文献
WO2007/119247 A2, ;
Page/Page column 23 ;
反应条件
hydrogen; Lindlar's catalyst in tetrahydrofuran T=40°C; P=131263 Torr;
参考文献
Advanced Synthesis and Catalysis, , vol. 349, # 17-18 p. 2655 - 2659
反应条件
phosphorous acid trimethyl ester in methanol
反应条件
palladium on graphite in N-methyl-acetamide; methanol
反应条件
Lindlar's catalyst in tetrahydrofuran T=120°C; P=131263 Torr; Title compound not separated from byproducts.;
参考文献
Advanced Synthesis and Catalysis, , vol. 349, # 17-18 p. 2655 - 2659
反应条件
potassium formiate; lithium chloride T=145 - 155°C; 10 h;
参考文献
WO2003/99761 A1, ;
Page 4; 10 ;
反应条件
tris(pentafluorophenyl)-borane; diisopropylamine T=100°C; 24 h; Neat (no solvent);
参考文献
Organometallics, , vol. 30, # 17 p. 4497 - 4500
反应条件
hydrogenchloride in methanol T=0 - 10°C; 2 h;
参考文献
UNICHEM LABORATORIES LIMITED
Patent: WO2007/119247 A2, 2007 ;
Location in patent: Page/Page column 23 ;
反应条件
hydrogenchloride in ethanol; water 12 h; Heating / reflux;
参考文献
STOHANDL, Jiri FRANTISEK, Jaroslav; ZAPADLO, Zdenek; STOHANDLOVA, Marta
Patent: WO2003/99761 A1, 2003 ;
Location in patent: Page 4; 10-11 ;
反应条件
in ethanol
T=15 - 55°C; Product distribution / selectivity;
参考文献
PIRAMAL HEALTHCARE LIMITED; PANDIT, Vilas Vasant; NAIK, Rajesh; KARNIK, Pravin; PAWAR, Nitin; SHAH, Pranay
Patent: WO2010/76763 A2, 2010 ;
Location in patent: Example 1 ;
