(S)-(-)-1-(2-溴苯基)乙胺合成路线 （共 5 条）
反应条件
tin(ll) chloride in tetrahydrofuran
参考文献
Brenchley, Guy; Fedouloff, Michael; Merifield, Eric; Wills, Martin
Tetrahedron Asymmetry, 1996 , vol. 7, # 10 p. 2809 - 2812
反应条件
1: With N-(2-hydroxybenzyl)amine; C24H34N2O2 in toluene T=110°C; 72 h; 2: With hydrogenchloride in tetrahydrofuran; water T=20°C; 24 h; Overall yield = 62 percent;
参考文献
Organic and Biomolecular Chemistry, , vol. 10, # 45 p. 8960 - 8962,3
Organic and Biomolecular Chemistry, , vol. 10, # 45 p. 8960 - 8962
反应条件
1: Ph2SiH2, <(COD)RhCl>2, chiral borane-benzazaphospole dimer / 0 °C 2: 82 percent / (PhO)2P(O)N3, DBU / tetrahydrofuran / 1.) RT, overnight, 2.) 45 deg C, 4 h 3: 83 percent / aq. SnCl2 / tetrahydrofuran View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 7, # 10 p. 2809 - 2812
反应条件
1: 82 percent / (PhO)2P(O)N3, DBU / tetrahydrofuran / 1.) RT, overnight, 2.) 45 deg C, 4 h 2: 83 percent / aq. SnCl2 / tetrahydrofuran View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 7, # 10 p. 2809 - 2812
反应条件
borane-THF; C19H23BNO3(1-)*H(1+) in 1,4-dioxane 72 h; Inert atmosphere; enantioselective reaction;
参考文献
Journal of Organic Chemistry, , vol. 78, # 11 p. 5314 - 5327
