1-羟基甲基-1-甲基环己烷合成路线 （共 32 条）
反应条件
lithium aluminium tetrahydride in diethyl ether 2 h; Ambient temperature;
参考文献
Shiner, V. J.; Tai, Jimmy J.
Journal of the American Chemical Society, 1981 , vol. 103, # 2 p. 436 - 442
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=0°C; Reduction;
参考文献
Takahashi, Masato; Dodo, Kosuke; Sugimoto, Yoshikazu; Aoyagi, Yoshimi; Yamada, Yuji; Hashimoto, Yuichi; Shirai, Ryuichi
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 22 p. 2571 - 2574
反应条件
kieselguhr; nickel T=90°C; P=73550.8 Torr; Hydrogenation;
参考文献
Journal of the American Chemical Society, , vol. 76, p. 771
反应条件
1: 92 percent / LDA / tetrahydrofuran / -78 °C 2: 80 percent / pyridine 3: LiAlH4 / tetrahydrofuran / 60 °C View Scheme
参考文献
Chemistry Letters, , p. 1785 - 1788
反应条件
hydrogenchloride; sodium borohydride in diethyl ether; ethanol
反应条件
1: 68 percent / 2N sulfuric acid / 8 h / Heating 2: 75 percent / n-BuLi, diisopropylamine / hexane; tetrahydrofuran / 1.) -78 deg C, 2.) -78 - 0 deg C, 3.) room temperature, 8 h 3: 75 percent / LiAlH4 / diethyl ether / 2 h / Ambient temperature View Scheme
参考文献
Journal of the American Chemical Society, , vol. 103, # 2 p. 436 - 442
反应条件
in toluene T=0°C; Alkylation; 1 h;
参考文献
Nishimura, Nanae; Mitsunobu, Oyo
Tetrahedron Letters, 2000 , vol. 41, # 16 p. 2945 - 2948
反应条件
1: H2 / Pd-C 2: LiAlH4 / diethyl ether View Scheme
参考文献
Journal of Organic Chemistry, , vol. 27, p. 2332 - 2338
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=60°C;
参考文献
Chemistry Letters, , p. 1785 - 1788
反应条件
mercury Irradiation;
参考文献
Brown, Stephen H.; Crabtree, Robert H.
Journal of the Chemical Society, Chemical Communications, 1987 , # 13 p. 970 - 971
