反应条件
1.1: triethylamine; diphenyl phosphoryl azide / toluene / 0.5 h / 80 °C
1.2: 3 h / Reflux
2.1: formic acid / 3 h / 50 °C / Inert atmosphere
3.1: 1,1'-carbonyldiimidazole / tetrahydrofuran / 0.17 h / 0 °C
3.2: 16 h / Inert atmosphere; Reflux
4.1: hydrogen / palladium-on-charcoal / water; tetrahydrofuran / 20 °C / 760.05 Torr
View Scheme
参考文献
CHEMO IBERICA, S.A.; RASPARINI, Marcello; TUFARO, Roberto Rocco; MINELLI, Cosima
Patent: WO2012/150328 A1, 2012 ;
