2-氨基噻吩-3-甲酰胺合成路线

参考文献

Smithkline Beecham Corporation
Patent: WO2003/104218 A1, 2003 ;
Location in patent: Page 13 ;
WO 03/104218 A1

14080-51-42-氨基噻吩-3-甲酰胺

参考文献

N.V. ORGANON
Patent: WO2008/3452 A1, 2008 ;
Location in patent: Page/Page column 42 ;
WO 2008/003452 A1

6851-93-0+

107-91-5氰乙酰胺

14080-51-42-氨基噻吩-3-甲酰胺

参考文献

Dumaitre, Bernard; Dodic, Nerina
Journal of Medicinal Chemistry, 1996 , vol. 39, # 8 p. 1635 - 1644

75-07-0乙醛+

107-91-5氰乙酰胺

14080-51-42-氨基噻吩-3-甲酰胺

参考文献

Bioorganic and Medicinal Chemistry Letters, , vol. 20, # 19 p. 5753 - 5756

14080-51-42-氨基噻吩-3-甲酰胺

4815-35-42-氨基-5-苯基-噻吩-3-羧酸胺

参考文献

Haidle, Andrew M.; Zabierek, Anna A.; Childers, Kaleen K.; Rosenstein, Craig; Mathur, Anjili; Altman, Michael D.; Chan, Grace; Xu, Lin; Bachman, Eric; Mo, Jan-Rung; Bouthillette, Melaney; Rush, Thomas; Tempest, Paul; Marshall, C. Gary; Young, Jonathan R.
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 8 p. 1968 - 1973

14080-51-42-氨基噻吩-3-甲酰胺+

57-13-6尿素

18740-38-02,4-二羟基噻吩[2,3-D]嘧啶

参考文献

Son, Hoon Young; Song, Yang-Heon
Bulletin of the Korean Chemical Society, 2010 , vol. 31, # 8 p. 2242 - 2246

14080-51-42-氨基噻吩-3-甲酰胺+

122-51-0原甲酸三乙酯

14080-50-3噻吩并[2,3-d]嘧啶-4(3H)-酮

参考文献

Pokhodylo, Nazariy T.; Shyyka, Olga Ya.; Savka, Roman D.; Obushak, Mykola D.
Phosphorus, Sulfur and Silicon and the Related Elements, 2010 , vol. 185, # 10 p. 2092 - 2100

14080-51-42-氨基噻吩-3-甲酰胺+

75-36-5乙酰氯

21582-51-44-羟基-2-甲基噻吩[2,3-D]嘧啶

参考文献

Robba,M. et al.
Comptes Rendus des Seances de l'Academie des Sciences, Serie C: Sciences Chimiques, 1968 , vol. 267, p. 697 - 700

1131-09-5苯并[b]噻吩-3-乙酸+

14080-51-42-氨基噻吩-3-甲酰胺

1246072-89-8

参考文献

De, Surya K.; Barile, Elisa; Chen, Vida; Stebbins, John L.; Cellitti, Jason F.; MacHleidt, Thomas; Carlson, Coby B.; Yang, Li; Dahl, Russell; Pellecchia, Maurizio
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 8 p. 2582 - 2588

14080-51-42-氨基噻吩-3-甲酰胺+

140-89-6乙基黄原酸钾

117516-97-92-硫氧代-2,3- 二氢噻吩并[2,3-d]嘧啶-4(1H)-酮

参考文献

Amgen Inc.
Patent: US2008/32988 A1, 2008 ;
Location in patent: Page/Page column 22 ;
US 20080032988 A1