(E)-3,7-二甲基-2,6-辛二烯醛合成路线 （共 128 条）
反应条件
1: 20 percent / Ca(OH)2 / methanol / 96 h / 0 °C
2: 42 percent / 1.5 M NaOH / H2O; methanol / 48 h / 45 °C
View Scheme
参考文献
Saimoto, Hiroyuki; Yoshida, Koji; Murakami, Tetsuya; Morimoto, Minoru; Sashiwa, Hitoshi; Shigemasa, Yoshihiro
Journal of Organic Chemistry, 1996 , vol. 61, # 20 p. 6768 - 6769
反应条件
1: 90 percent / LiN(SiMe3)2 / toluene
2: 1.) mCPBA, 2.) Al(i-PrO)3 / 2.) toluene, reflux
3: 85 percent / 2,4-dinitrophenol / toluene / Heating
4: 98 percent / D-glucose / ethanol; H2O / 48 h / Ambient temperature; baker's yeast
5: pyridine
6: 1.) POCl3, pyridine, 2.) LiOH / 2.) MeOH
7: 1.) DIBAH, 2.) (COOH)2, 3.) DIBAH
8: 1.) CCl3CN, NaH, 2.) p-TsOH / 2.) pentane
9: 92 percent / t-BuLi / tetrahydrofuran / -78 - 0 °C
View Scheme
参考文献
Kodama, Mitsuaki; Yoshio, Suzuyo; Yamaguchi, Shinji; Fukuyama, Yoshiyasu; Takayanagi, Hisao; et al.
Tetrahedron Letters, 1993 , vol. 34, # 52 p. 8453 - 8456
反应条件
1: piperidine
2: NaBH4 / methanol
3: pyridine
View Scheme
参考文献
Jacob, L.; Julia, M.; Pfeiffer, B.; Rolando, C.
Bulletin de la Societe Chimique de France, 1990 , # 6 p. 719 - 733
反应条件
1: CHCl3 / 0.25 h / Ambient temperature
2: K2CO3 / methanol / 3 h / Heating
View Scheme
参考文献
Arbones, Cesar; Sanchez, Francisco J.; Marco, Maria-Pilar; Camps, Francisco; Messeguer, Angel
Heterocycles, 1990 , vol. 31, # 1 p. 67 - 78
反应条件
sodium hydroxide; silver nitrate in methanol; water
T=55 - 56°C; 0.75 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Valentine Jr.; Johnson; Priester; et al.
Journal of Organic Chemistry, 1980 , vol. 45, # 18 p. 3698 - 3703
反应条件
1: 93 percent / Ag2O, aq. NaOH / 8 h
2: 99percent HCO2H / 0.33 h / Heating
View Scheme
参考文献
Kadas, Istvan; Arvai, Geza; Horyath, Gabriella
Organic Preparations and Procedures International, 1998 , vol. 30, # 1 p. 79 - 85
反应条件
1: aq. H2SO4
2: NaBH4
3: PBr3
4: dimethylsulfoxide
5: aq. KOH
View Scheme
参考文献
Bhar, Shanta S.; Ramana
Journal of Organic Chemistry, 2004 , vol. 69, # 25 p. 8935 - 8937
反应条件
1: 93 percent / Ag2O, aq. NaOH / 8 h
2: 59 percent / 99percent HCO2H / 0.33 h / Heating
View Scheme
参考文献
Kadas, Istvan; Arvai, Geza; Horyath, Gabriella
Organic Preparations and Procedures International, 1998 , vol. 30, # 1 p. 79 - 85
反应条件
1: aq. H2SO4
2: NaBH4
3: PBr3
4: dimethylsulfoxide
View Scheme
参考文献
Bhar, Shanta S.; Ramana
Journal of Organic Chemistry, 2004 , vol. 69, # 25 p. 8935 - 8937
反应条件
ethylenediamine diacetic acid in methanol
T=20°C; 1 h;
参考文献
Tietze, Lutz-F.; Kiedrowski, Guenter v.; Berger, Bernhard
Synthesis, 1982 , # 8 p. 683 - 684
