Baker, William R.; Fung, Anthony K. L.; Kleinert, Hollis D.; Stein, Herman H.; Plattner, Jacob J.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 10 p. 1722 - 1734
1: 1.) NaH / 1.) THF, RT, 2 h, 2.) THF, RT, 16 h
2: KOH / H2O / 24 h / Heating
View Scheme
参考文献
Baker, William R.; Fung, Anthony K. L.; Kleinert, Hollis D.; Stein, Herman H.; Plattner, Jacob J.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 10 p. 1722 - 1734
1: 1.) NaH / 1.) THF, -60 deg C, 2.) THF, from -60 deg C to RT, overnight
2: KOH / H2O / 24 h / Heating
View Scheme
参考文献
Baker, William R.; Fung, Anthony K. L.; Kleinert, Hollis D.; Stein, Herman H.; Plattner, Jacob J.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 10 p. 1722 - 1734