2-[(4-甲基苯基)亚甲基丙二酸二乙酯合成路线 （共 11 条）
反应条件
piperidine in benzene 18 h; Heating;
参考文献
Almansa, Carmen; Gomez, Luis A.; Cavalcanti, Fernando L.; De Arriba, Alberto F.; Rodriguez, Ricardo; Carceller, Elena; Garcia-Rafanell, Julian; Forn, Javier
Journal of Medicinal Chemistry, 1996 , vol. 39, # 11 p. 2197 - 2206
反应条件
ytterbium(III) perfluorooctanesulfonate in toluene T=80°C; Knoevenagel condensation; 12 h;
参考文献
Yi, Wen-Bin; Yin, Ya-Qing; Cai, Chun
Organic Preparations and Procedures International, 2007 , vol. 39, # 1 p. 71 - 75
反应条件
4-(N,N-dimethlyamino)pyridine T=80 - 85°C; Knoevenagel condensation; 4 h;
参考文献
Narsaiah, A. Venkat; Basak; Visali; Nagaiah
Synthetic Communications, 2004 , vol. 34, # 16 p. 2893 - 2901
反应条件
in dichloromethane Irradiation;
参考文献
Journal of Organic Chemistry, , vol. 61, # 18 p. 6233 - 6239
反应条件
in dichloromethane Ambient temperatureIrradiation;
参考文献
Tetrahedron Letters, , vol. 36, # 44 p. 8039 - 8042
反应条件
1: 97 percent / SiCl4 / CH2Cl2 / Ambient temperature 2: 72 percent / copper acetylacetonate / benzene / 48 h / Heating 3: 91 percent / CH2Cl2 / Irradiation View Scheme
参考文献
Journal of Organic Chemistry, , vol. 61, # 18 p. 6233 - 6239
反应条件
1: 72 percent / copper acetylacetonate / benzene / 48 h / Heating 2: 91 percent / CH2Cl2 / Irradiation View Scheme
参考文献
Journal of Organic Chemistry, , vol. 61, # 18 p. 6233 - 6239
反应条件
aluminium trichloride in 1,2-dichloro-ethane
参考文献
Chemische Berichte, , vol. 110, p. 86 - 95
反应条件
1: 2-(4-methylbenzyl)malonic acid diethyl ester With potassium hydride in acetonitrile T=20°C; 0.333333 h; Inert atmosphereGlovebox; 2: 4-acetylamino-2,2,6,6-tetramethylpiperidine-1-oxoammonium in acetonitrile T=24.84°C; Inert atmosphereGlovebox; Thermodynamic data;
参考文献
Journal of Organic Chemistry, , vol. 78, # 14 p. 7154 - 7168
反应条件
triethyl amine hydrochloride T=180°C; 3.5 h;
参考文献
Ohno; Mizukoshi; Izumi; Kato; Hori
Chemical and Pharmaceutical Bulletin, 1988 , vol. 36, # 2 p. 551 - 562
