tetrabutyl ammonium fluoride in tetrahydrofuran 3 h; Ambient temperature;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1731462', constants.ctx, '0')">triethyl borane</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '3587329', constants.ctx, '0')">tri-n-butyl-tin hydride</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1730733', constants.ctx, '0')">hexane</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '969212', constants.ctx, '0')">benzene</a> <br />&nbsp;Ambient temperature;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 1) hexamethyldisilazane (HMDS), ammonium sulfate, 2) trimethylsilyl triflate (TMSOTf) / 1) reflux, 2 h, 2) 1,2-dichlorethane, a) 5 deg C, 10 min, b) room temperature, 10 min<br />2: 81.1 percent / n-Bu₃SnH, Et₃B / benzene; hexane / Ambient temperature<br /> <br /> &nbsp;

<b>Multi-step reaction with 6 steps<br /> </b>1: 1) lithium hexamethyldisilazide / 1) THF, -78 deg C, 1h, 2) room temperature, 30 min<br />2: tetrahydrofuran / -78 &deg;C<br />3: DIBAL-H / toluene / 2 h / -78 &deg;C<br />4: 96 percent / pyridine, DMAP / CH₂Cl₂ / 2 h / 0 &deg;C<br />5: 1) hexamethyldisilazane (HMDS), ammonium sulfate, 2) trimethylsilyl triflate (TMSOTf) / 1) reflux, 2 h, 2) 1,2-dichlorethane, a) 5 deg C, 10 min, b) room temperature, 10 min<br />6: 81.1 percent / n-Bu₃SnH, Et₃B / benzene; hexane / Ambient temperature<br /> <br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>1: DIBAL-H / toluene / 2 h / -78 &deg;C<br />2: 96 percent / pyridine, DMAP / CH₂Cl₂ / 2 h / 0 &deg;C<br />3: 1) hexamethyldisilazane (HMDS), ammonium sulfate, 2) trimethylsilyl triflate (TMSOTf) / 1) reflux, 2 h, 2) 1,2-dichlorethane, a) 5 deg C, 10 min, b) room temperature, 10 min<br />4: 81.1 percent / n-Bu₃SnH, Et₃B / benzene; hexane / Ambient temperature<br /> <br /> &nbsp;

<b>Multi-step reaction with 7 steps<br /> </b>1: 98 percent / imidazole / dimethylformamide / 1 h / Ambient temperature<br />2: 1) lithium hexamethyldisilazide / 1) THF, -78 deg C, 1h, 2) room temperature, 30 min<br />3: tetrahydrofuran / -78 &deg;C<br />4: DIBAL-H / toluene / 2 h / -78 &deg;C<br />5: 96 percent / pyridine, DMAP / CH₂Cl₂ / 2 h / 0 &deg;C<br />6: 1) hexamethyldisilazane (HMDS), ammonium sulfate, 2) trimethylsilyl triflate (TMSOTf) / 1) reflux, 2 h, 2) 1,2-dichlorethane, a) 5 deg C, 10 min, b) room temperature, 10 min<br />7: 81.1 percent / n-Bu₃SnH, Et₃B / benzene; hexane / Ambient temperature<br /> <br /> &nbsp;