(R)-3-甲基 3,4-二氢异喹啉盐酸盐合成路线 （共 4 条）
反应条件
1,2,3,4-tetrahydro-naphthalene; phosphorus pentoxide
参考文献
Caroon, Joan M.; Clark, Robin D.; Kluge, Arthur F.; Lee, Chi-Ho; Strosberg, Arthur M.
Journal of Medicinal Chemistry, 1983 , vol. 26, # 10 p. 1426 - 1433
反应条件
1: 5 h / 160 °C 2: polyphosphoric acid (PPA) / 4 h / 150 °C View Scheme
参考文献
Caroon, Joan M.; Clark, Robin D.; Kluge, Arthur F.; Lee, Chi-Ho; Strosberg, Arthur M.
Journal of Medicinal Chemistry, 1983 , vol. 26, # 10 p. 1426 - 1433
反应条件
1: Raney nickel; ethanolic NH3 / Hydrogenation 2: phosphorus (V)-oxide; tetralin View Scheme
参考文献
Gibson
Journal of the Chemical Society, 1956 , p. 808,809
反应条件
palladium on activated charcoal T=220°C;
参考文献
Gibson
Journal of the Chemical Society, 1956 , p. 808,809
