4-(4-甲酰基-2-甲氧基苯氧基)丁酸乙酯合成路线 (共 3 条)
反应条件
potassium carbonate in N,N-dimethyl-formamide T=80°C; 48 h; Inert atmosphere;
参考文献
Shi, Qian; Wada, Koji; Ohkoshi, Emika; Lin, Li; Huang, Rong; Morris-Natschke, Susan L.; Goto, Masuo; Lee, Kuo-Hsiung
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 13 p. 4020 - 4031
参考文献
SmithKline Beecham Corporation
Patent: US5393788 A1, 1995 ;
US 5393788 A
反应条件
1: nitric acid / 0 - 20 °C / Inert atmosphere 2: trifluoroacetic acid / water / 3 h / 90 °C / Inert atmosphere 3: sodium tetrahydroborate / 12 h / 0 - 20 °C / Inert atmosphere View Scheme
参考文献
Griffin, Donald R.; Kasko, Andrea M.
Journal of the American Chemical Society, 2012 , vol. 134, # 42 p. 17833 - 17833